Genetic Testing May Benefit Older Women with Breast Cancer

About 1 in 40 postmenopausal women diagnosed with breast cancer before age 65 have cancer-associated mutations in their BRCA1 or BRCA2 genes, according to a Stanford-led study of more than 4,500 participants in the long-running Women’s Health Initiative. The prevalence of the mutations in this group is similar to that of Ashkenazi Jewish women, whom […]

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Blood Sample Detects Prostate Cancer ‘Fingerprint’

Scientists at UCL have invented a new test to identify the earliest genetic changes of prostate cancer in blood: a process which could allow doctors to see if cancers have spread, monitor tumour behaviour and enable better treatment selection. In the study, published in The Journal of Clinical Investigation, researchers at UCL Cancer Institute used […]

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High Mortality in Older Adults Linked to Low Blood Pressure

A large scale study led by the University of Exeter, published in Age and Ageing and funded by NIHR, analysed 415,980 electronic medical records of older adults in England. The research was conducted after some countries have changed blood pressure guidelines to encourage clinicians to take measures to reduce blood pressure in a bid to […]

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Risk of Rare Kidney Cancer Coming Back Cut in Half with Chemotherapy After Surgery

Chemotherapy halves the risk of a rare form of kidney cancer coming back after surgery, the largest ever trial conducted in the disease worldwide has found. Patients given chemotherapy within three months of surgery saw the risk of their cancer coming back or spreading reduced and were much more likely to live cancer free for […]

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Cardiovascular Disease Linked to a New Diet-Associated Gut-Microbe Metabolite

Cleveland Clinic researchers have identified a gut microbe generated byproduct – phenylacetylglutamine (PAG) – that is linked to development of cardiovascular disease, including heart attack, stroke and death. The study was published in Cell. Phenylalanine is an amino acid found in many foods, including plant- and animal-based protein sources like meat, beans and soy. The […]

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The Reliability of Common Autistic Personality Test Being Questioned

Psychologists at the University of Bath, King’s College London, and Cardiff University have found that a common test used by doctors and researchers to measure autistic personality traits lacks reliability and might not be capturing the right signs of autism. This means that research including scores from this test may lack validity and raises new […]

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